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The Goal Of A Uk Trial Is To Uncover Concealed Lung Damage Induced By Extended Covid Exposure

A clinical investigation has begun to identify currently undetectable lung damage in persons with lengthy Covid, as part of a PS20 million research effort aimed at eradicating the condition’s stigma.
Patients who are still experiencing breathlessness will be drawn from long lines at Covid clinics in Sheffield, Manchester, and Cardiff to receive xenon gas scans, which will reveal damage that isn’t seen on standard CT scans, solving the puzzle of why individuals aren’t getting better.
The National Institute for Health Research is funding 15 studies, including one by Fergus Gleeson, a professor of radiology at the University of Oxford, that will look at why the virus produces “brain fog” and how much it costs the NHS and businesses whose staff are unable to work.
Long Covid is described as experiencing one or more Covid symptoms for more than 12 weeks, including weariness, muscle soreness, and diarrhoea, and is thought to impact more than 2 million people.
Prof Nick Lemoine, the institute’s medical director, said the funding will more than double the institute’s current research funding into the disease, with a series of “quite large-scale investigations to characterize the disease and better understand it.”
One of the trials will look at the efficacy of several medications, including aspirin, in approximately 4,500 individuals from six cities.
According to Dr. Amitava Banerjee, an associate professor of clinical data analytics at University College London (UCL), it will look at “surprising findings of modest organ damage across many organs.”
“All of the long Covid clinics that have been built up have waiting lists,” Banerjee said when asked about public misgivings about the seriousness of the illness, which appears in a variety of ways ranging from cognitive impairment to dyspnea.
This is undeniable and far from fictitious.” 11:06 Inside a long Covid clinic: I appear normal, but my body is breaking down – video Another study will look at long Covid’s cognitive profile to see if it impacts memory or decision-making speed, as well as whether cognitive rehabilitation, as used in stroke victims, can help.
Dr Dennis Chan, a principal research fellow at UCL, will lead a trial of app-based therapy and will also conduct brain scans to investigate how brain volume changes and connections are impacted as a result of the virus directly accessing neuronal circuits.
One of the issues facing studies is evaluating extended Covid in persons who have not been hospitalized and deciding whether hospital clinics or general practitioners are best suited to deal with the problem.
It had already been proven, according to Lemoine, that middle-aged adults, particularly women, were more prone to have long Covids.
According to a University of Birmingham study, those who experienced more than five symptoms in the first week of having the virus were more likely to develop it.
The prevalence of long Covid in that cohort is smaller than in middle-aged or elderly persons, according to results from an ongoing research of more than 10,000 school-age children and young adults who had received a positive diagnosis, which could be good news for younger people.

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